γ-[(8-Aminooctyl)-imido]-ATP

NUCLEOTIDE ANALOG · BIOCHEMISTRY · MOLECULAR BIOLOGY

γ-[(8-Aminooctyl)-imido]-ATP

γ-[(8-Aminooctyl)-imido]-adenosine-5′-triphosphate, sodium salt, is a modified ATP analog designed for biochemical research involving nucleotide interactions and protein purification.

Available Sizes: 100 µL and 5 × 100 µL Concentration: 10–11 mM

Product Overview

γ-[(8-Aminooctyl)-imido]-ATP is a chemically modified adenosine-5′-triphosphate analog containing an 8-aminooctyl substituent linked through a phosphoramidate-type modification. It is supplied as a sodium salt in aqueous solution for general laboratory use.

Modified nucleotide analogs are valuable tools in biochemical research because their structural modifications can provide additional functionality for studying nucleotide-binding proteins, enzyme interactions, and molecular recognition. The aminated alkyl chain in this compound may be relevant to investigations involving nucleotide immobilization and affinity-based approaches, depending on the experimental design.

This compound has been discussed in research on γ-phosphate-linked nucleoside affinity chromatography materials, including applications related to protein purification and ribonucleoside triphosphate reductase. Consult the relevant literature and experimental protocols to determine its suitability for a specific application.

Key Product Features

  • Product: γ-[(8-Aminooctyl)-imido]-ATP.
  • Full chemical name: γ-[(8-Aminooctyl)-imido]-adenosine-5′-triphosphate, sodium salt.
  • Product type: Modified nucleotide analog.
  • Purity: ≥ 95% by HPLC.
  • Concentration: 10–11 mM.
  • Formulation: Aqueous solution.
  • Appearance: Colorless to slightly yellow.
  • Storage: −20 °C.
  • Intended use: General laboratory research.

Available Sizes

Pack Size Concentration Total Volume
100 µL 10 mM 100 µL
5 × 100 µL 10 mM 500 µL total

Technical Specifications

Product Name γ-[(8-Aminooctyl)-imido]-ATP
Full Chemical Name γ-[(8-Aminooctyl)-imido]-adenosine-5′-triphosphate, sodium salt
Molecular Formula C₁₈H₃₄N₇O₁₂P₃ (free acid)
Molecular Weight 633.43 g/mol (free acid)
Exact Mass 633.15 g/mol (free acid)
Purity ≥ 95% (HPLC)
Form Solution in water
Color Colorless to slightly yellow
Concentration 10–11 mM
pH 7.5 ± 0.5
Maximum Absorbance (λmax) 259 nm
Molar Absorption Coefficient 15.4 L mmol⁻¹ cm⁻¹ (Tris-HCl, pH 7.5)
Shipping Conditions Shipped on gel packs
Storage Temperature −20 °C
Shelf Life 12 months after delivery

Research Applications

  • Biochemical studies of modified ATP analogs and nucleotide-protein interactions.
  • Research into nucleotide-binding proteins and enzyme recognition.
  • Development and investigation of γ-phosphate-linked nucleoside affinity chromatography materials.
  • Exploration of affinity-based protein purification strategies.
  • Research involving ribonucleoside triphosphate reductase and related nucleotide-binding systems.

Application note: Specific assay protocols, binding conditions, and performance characteristics should be established for the intended experimental system. The applications listed above describe research areas and do not imply validation for every assay.

Stability and Handling

Recommended Storage: Store at −20 °C.

Shipping: The product is shipped on gel packs.

Ambient Temperature: Short-term exposure, up to one week cumulatively, is permitted according to the supplied product information.

Shelf Life: 12 months after the date of delivery.

Important Chemical Stability Note

pH Sensitivity

This compound contains a phosphoramide linkage that is hydrolyzed at pH below 7.0. Maintain appropriate pH conditions during handling and experimental use to help preserve compound integrity. The supplied product information specifies a pH of 7.5 ± 0.5.

Selected Reference

Suto et al. (1998). Synthesis of γ-phosphate-linked nucleoside affinity chromatography resins for protein purification, including ribonucleoside triphosphate reductase. Nucleosides and Nucleotides, 17(8), 1453.

Ordering Information

Product: γ-[(8-Aminooctyl)-imido]-ATP

Available Pack Sizes: 100 µL or 5 × 100 µL

Concentration: 10 mM (nominal; stated range 10–11 mM)

Intended Use: General laboratory research.

Research Use Disclaimer

For general laboratory research use only. This product is intended for laboratory research and is not represented as a diagnostic, therapeutic, food, or human-use product. Follow the supplier's documentation for storage, handling, and experimental procedures.

19th Oct 2026

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